Cascading regulation of histidase activity in Streptomyces griseus
نویسندگان
چکیده
منابع مشابه
Purification of histidase from Streptomyces griseus and nucleotide sequence of the hutH structural gene.
Histidine ammonia-lyase (histidase) was purified to homogeneity from vegetative mycelia of Streptomyces griseus. The enzyme was specific for L-histidine and showed no activity against the substrate analog, D-histidine. Histidinol phosphate was a potent competitive inhibitor. Histidase displayed saturation kinetics with no detectable sigmoidal response. Neither thiol reagents nor a variety of di...
متن کاملDecision phase regulation of streptomycin production in Streptomyces griseus
lnstitut fur Chemische M i k ro biolog ie, Berg isc h e Universitat GH Wuppertal, Gauss-Str. 20, 421 09 Wuppertal, Germany The streptomycin (Sm) producer, Streptomyces griseus N2-3-11, shows medium-independent biphasic kinetics of the vegetative or exponential growth phase (EGP), reflecting an innate clock-like behaviour of growth and differentiation. The 5. griseus growth and development cycle...
متن کاملOxidation of Meloxicam by Streptomyces griseus
The aim of the present investigation was to biotransform the anti-inflammatory compound meloxicam by enzymes present in whole cells of five actinomycete cultures to produce novel bioactive derivatives. Among the actinomycetes screened, Streptomyces griseus NCIM 2622 was found to possess the enzyme system(s) that oxidize meloxicam into two metabolites whereas that present in S. griseus NCIM 2623...
متن کاملCharacterization of Ca2+-ATPase activity in Streptomyces griseus.
Ca2+-ATPase activity has been characterized in Streptomyces griseus. The enzyme has a pH optimum of 8.5 at 37 degrees C. Its Ca2+ requirement can be substituted by Cd2+, Zn2+ and Mn2+. Mg2+ inhibits the enzyme non-competitively.
متن کاملDifferential regulation of ftsZ transcription during septation of Streptomyces griseus.
Streptomyces has been known to form two types of septa. The data in this research demonstrated that Streptomyces griseus forms another type of septum near the base of sporogenic hyphae (basal septum). To understand the regulation of the septation machinery in S. griseus, we investigated the expression of the ftsZ gene. S1 nuclease protection assays revealed that four ftsZ transcripts were diffe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1989
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.171.2.1100-1105.1989